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BASIC SCIENCES REVIEW
Year : 2006  |  Volume : 3  |  Issue : 1  |  Page : 14-19

Effect of fluoride on thyroid functions: Myths and facts


1 Assistant Professor, Department of Biochemistry, Amrita Institute of Medical Sciences, Elamakkara P.O., Cochin 682 026, India
2 Professor and Head, Department of Biochemistry, Amrita Institute of Medical Sciences, Elamakkara P.O., Cochin 682 026, India
3 Scientist, Department of Physiology, Dr. P. Siddhartha Institute of Medical Sciences, Chinoutpalli, Gannavaram, Krishna District, A.P 521 286, India

Correspondence Address:
S K Das
Assistant Professor, Department of Biochemistry, Amrita Institute of Medical Sciences, Elamakkara P.O., Cochin 682 026
India
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Source of Support: None, Conflict of Interest: None


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The widespread use of fluoride to reduce dental caries has aroused considerable controversy. Fluoride is toxic when consumed in excessive amounts. Industrial fluorosis is on the increase on a global basis. While some researchers have concluded that fluoride has no effect on the thyroglobulin content of the thyroid gland or the degree of iodination of thyroglobulin, others have shown that adverse changes occur with higher intakes of drinking water in endemic fluorosis areas or with fluoride treatment.


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