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ORIGINAL ARTICLE
Year : 2007  |  Volume : 4  |  Issue : 1  |  Page : 10-12

Bone mineral density in patients with hyperthyroid Graves' disease - a pilot study


1 Department of Endocrinology,All India Institute of Medical Sciences, New Delhi, India
2 Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
V P Jyotsna
Department of Endocrinology,All India Institute of Medical Sciences, New Delhi
India
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Source of Support: None, Conflict of Interest: None


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Osteopenia and vitamin D deficiency are known to be associated with hyperthyroidism. Some studies suggest that serum 25-hydroxy vitamin D may be monitored in patients with Graves' disease during antithyroid drug therapy and vitamin D and calcium supplementation are recommended for patients with vitamin D deficiency. Few studies have suggested that prophylaxis for osteoporosis is appropriate for patients who have hyperthyroid disorder with assessment of bone mineral density and perhaps pharmacological therapy for those with additional risk factors. But there is still no consensus about screening of Graves' patients for vitamin D deficiency/osteopenia and it's prophylaxis and treatment. This is a preliminary study to evaluate bone health in patients of hyperthyroid Graves' disease. We measured the bone mineral density in 14 patients of Graves' disease and compared it to normal age and sexmatched controls. The bone mineral density was found to be significantly low at forearm and spine compared to normal healthy population.


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