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ORIGINAL ARTICLE
Year : 2007  |  Volume : 4  |  Issue : 3  |  Page : 78-81

Sexual dysfunction persists in well-controlled hypothyroid women


Department of Endocrinology, Bharti hospital, Karnal, Hariyana, India

Correspondence Address:
S Kalra
Department of Endocrinology, Bharti hospital, Karnal, Hariyana
India
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Source of Support: None, Conflict of Interest: None


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This cross sectional, observational, non-interventional study has assessed the incidence of sexual dysfunction, and the effect of thyroxine replacement on sexual function in hypothyroid women. Female Sexual Function Index (FSFI) questionnaire was administered to 120 women with well-controlled hypothyroidism (serum TSH level 0.51 - 5.00, mean 3.36 ± 2.41 mU/L) and 30 with uncontrolled (serum TSH level 8.26 - 24.26, mean 12.20 ± 4.80 mU/L) hypothyroidism. Control consisted of 120 women with no obvious endocrinopathy. Uncontrolled subjects scored lower than controls in domains of desire (2.40 ± 0.88 vs. 3.80 ± 1.43; p<0.01), arousal (2.50 ± 1.70 vs. 4.07 ± 1.11; p<0.01), orgasm (2.90 ± 2.32 vs. 5.30 ± 0.68; p<0.01), satisfaction (4.50 ± 2.28 vs. 5.80 ± 0.60; p<0.05) and total score (30.66 ± 29.34 vs. 76.60 ± 10.10, p<0.001). Well- controlled patients scored less than controls in all domains, with significant difference in orgasm (4.50 ± 0.87 vs. 5.30 ± 0.68; p<0.05) and total score (58.30 ± 26.56 vs. 76.60 ± 10.10; p<0.05). Well-controlled subjects scored higher than uncontrolled subjects only in lubrication (4.70 ± 0.63 vs. 2.40 ± 2.14; p<0.001), orgasm (4.50 ± 0.87 vs. 2.90 ± 2.32; p<0.05) and total score (58.30 ± 26.56 vs. 30.66 ± 29.34; p<0.05). There was no correlation of FSFI scores with age, duration of hypothyroidism, years of marriage or TSH levels. This study highlights the prevalence of sexual dysfunction in hypothyroid women. This dysfunction, especially orgasm disorder, persists after optimal thyroxine supplementation.


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