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CASE REPORT
Year : 2008  |  Volume : 5  |  Issue : 1  |  Page : 18-21

Thyrotoxicosis, epilepsy and psychosis: A rare combination!


Department of Endocrinology and Metabolism, Sheri-Kashmir Institute of Medical Sciences, Soura Srinagar J&k, India; Department of Psychiatry, Universal College of Medical Sciences, PB 53,Ranigoan, Bairahawa, Nepal

Correspondence Address:
M A Ganie
Department of Endocrinology and Metabolism, Sheri-Kashmir Institute of Medical Sciences, Soura Srinagar J&k, India; Department of Psychiatry, Universal College of Medical Sciences, PB 53,Ranigoan, Bairahawa, Nepal

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Source of Support: None, Conflict of Interest: None


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An adolescent female experienced 9 episodes of brief cyclic illness during a period of 15 months, with most attacks being during menstrual period. Each episode used to last 4 to 8 days presenting with symptoms of acute psychosis. After 2-3 days patient would experience a generalised seizure. Following these acute episodes violent psychotic behaviour would subside; patient would remain alone, aloof and muttered to self. All symptoms would subside by 4 to 8 days and the patient would return to a state of partial normalcy. CT, MRI, EEG, revealed no abnormality. Initial thyroid function tests report was suggestive of thyrotoxicosis. Antithyroid medications for a short period lead to complete state of normalcy. After nine months of follow-up patient is doing well with no further psychosis or seizure attack.


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