Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online: 657


CASE REPORT
Year : 2008  |  Volume : 5  |  Issue : 2  |  Page : 48-50

Grave's disease - HAART induced immune reconstitution syndrome


Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India

Correspondence Address:
A Bhattacharyya
Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Highly Active Anti Retroviral Therapy (HAART) for the treatment of HIV causes a paradoxical deterioration of the clinical status after it's initiation, due to the reactivation of immune response to a latent or sub-clinical process. This phenomenon is called Immune Reconstitution Syndromes (1RS). We report a 48-year old man with HIV infection who was started on combination antiretroviral therapy. Three years after the initiation of therapy, he developed symptoms and signs of thyrotoxicosis. He was diagnosd to have Graves ' disease and was started on beta blockers and Neomercazole. Radioactive iodine was given after a good clinical and biochemical improvement. He became hypothyroid and currently doing well on replacement therapy. Immune reconstitution syndrome Grave's disease may appear months or even years after the initiation of antiretroviral therapy. As there is a high chance of relapse with anti-thyroid drugs, radioiodine ablation probably is more appropriate treatment in this condition after initial stabilization of thyrotoxicosis with anti-thyroid drugs


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed725    
    Printed81    
    Emailed0    
    PDF Downloaded195    
    Comments [Add]    

Recommend this journal