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REVIEW ARTICLE
Year : 2009  |  Volume : 6  |  Issue : 1  |  Page : 6-11

Management of maternal hypothyroidism: A practical perspective


Department of Endocrinology and Diabetes, Amrita Institute of Medical Sciences, Elamakkara, Cochin 682026, India

Correspondence Address:
A G Unnikrishnan
Department of Endocrinology and Diabetes, Amrita Institute of Medical Sciences, Elamakkara, Cochin 682026
India
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Source of Support: None, Conflict of Interest: None


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The occurrence of Hypothyroidism in pregnancy is linked to adverse effects on mother and the fetus. Recent research has indicated that in the first half of pregnancy, an adequate thyroid hormone level could play an important role in fetal brain development. Clinical signs of hypothyroidism in pregnancy are not very specific and sensitive. Therefore, serum TSH estimation is the best way to make a diagnosis. Hypothyroidism in pregnancy, whether overt or subclinical, requires therapy with levothyroxine. Frequent monitoring and precise dose titration are required. The aim of therapy is to achieve a TSH value that is < 2.5 mu/L, and this is important to ensure a successful pregnancy outcome.


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