Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online: 220


CASE REPORT
Year : 2010  |  Volume : 7  |  Issue : 2  |  Page : 52-57

Thyroid stimulating hormone (TSH) -secreting pituitary adenoma presenting as hyperthyroidism


1 Endocrinology Advanced Trainee, Department of Endocrinology and Diabetes, The Townsville Hospital, Townsville, Queensland 4814; Adjunct Lecture, School of Medicine and Dentistry, James Cook University, Townsville, Queensland 4811, Australia
2 Consultant Physician and Endocrinologist, Department of Endocrinology and Diabetes, Cairns Base Hospital, Cairns, Queensland 4870, Australia
3 Consultant Endocrinologist, Department of Endocrinology and Diabetes, Cairns Base Hospital, Cairns, Queensland 4870; Adjunct Associate Professor, School of Medicine and Dentistry, James Cook University, Cairns, Queensland 4878, Australia

Correspondence Address:
S K Chaubey
Endocrinology Advanced Trainee, Department of Endocrinology and Diabetes, The Townsville Hospital, Townsville, Queensland 4814; Adjunct Lecture, School of Medicine and Dentistry, James Cook University, Townsville, Queensland 4811
Australia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Graves ' disease was diagnosed in a patient in the community . Clinical and biochemical thyrotoxicosis persisted on anti thyroid drug (ATD) Carbimazole treatment and thyroid function tests showed inappropriately normal TSH with raised free T' and free T . After methodological interferences were ruled out, TSH-secreting pituitary adenoma or thyroid hormone resistance was suspected. After further biochemical and radiological investigations including free alpha glycoprotein subunit (SL-GSU) measurement and MB! scan of brain a diagnosis TSH secreting macro adenoma was suggested. She underwent debulking surgery and immunohistochemical staining confirmed a benign pituitary tumor with positive staining for TSH and Luteinizing hormone (LH). She received pre and post operative octreotide injections. Post operatively pituitary radiation treatment was given with which her disease had stabilized and she had marked clinical and investigational improvement.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed848    
    Printed53    
    Emailed0    
    PDF Downloaded218    
    Comments [Add]    

Recommend this journal