Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online: 246


ORIGINAL ARTICLE
Year : 2011  |  Volume : 8  |  Issue : 2  |  Page : 13-16

Prevalence of Anti thyroid peroxidase (Anti TPO) in type 1 diabetes mellitus:


1 Department of Biochemistry, Amrita Institute of Medical Sciences, AIMS, Ponekkara P.O., Cochin - 682 041, Kerala, India
2 Department of Endocrinology, Amrita Institute of Medical Sciences, AIMS, Ponekkara P.O., Cochin - 682 041, Kerala, India

Correspondence Address:
A G Unnikrishnan
Department of Endocrinology, Amrita Institute of Medical Sciences, AIMS, Ponekkara P.O., Cochin - 682 041, Kerala
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Aims:  The aim of our study was to determine the prevalence of anti-thyroid peroxidase (anti-TPO) and tyrosine phosphatase (IA2) antibodies positivity in glutamic acid decarboxylase (GAD65) antibody positive type 1 diabetics. Methods:  Seventy five type 1 diabetic patients with GAD65+ve were included in this hospital based study. IA -2 and Anti TPO antibodies were measured in this cohort Results:  In GAD65 +ve Type 1 diabetics the TPO antibody positivity was found in 58.7%(44/75) patients, Females had higher prevalence of TPO antibodies positive than the males(73% vs. 44.7%, P = 0.019). Positive IA-2A is present in 68.2 % males and 55.5 % females in Type 1 diabetic patients who were Gad 65 positivity. Conclusions:  There is a high prevalence of Anti TPO positivity in our Type 1 diabetic patients who are Gad 65 positive. So thyroid autoimmunity should be screened at diagnosis in all our Type 1 diabetic patients.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1042    
    Printed66    
    Emailed1    
    PDF Downloaded244    
    Comments [Add]    

Recommend this journal