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CASE REPORT
Year : 2014  |  Volume : 11  |  Issue : 1  |  Page : 35-37

Pellagra and hypothyroidism: A rare combination


Department of Medicine, Padmashree Dr. D. Y Patil Medical College, Hospital and Research Center, Pune, Maharashtra, India

Correspondence Address:
Arvind Bamanikar
Department of Medicine, Padmashree Dr. D. Y Patil Medical College, Hospital and Research Center, Pune, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-0354.124195

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Pellagra is more common in developing countries than the rest of the world. Malnutrition is more common in these countries; in part because the staple grains do not have sufficient niacin. Classical triad of diarrhoea, dermatitis, and dementia is diagnostic of pellagra. Milder forms can present with slowing of mental functions and skin manifestations can start as dryness of skin Castle's necklace and glove; stocking pattern of dermatitis. We had a female patient who was operated for thyroid disease in the past but was not on replacement therapy. Hypothyroidism and pellagra were diagnosed to be present simultaneously, which is reported very rarely. Both the conditions presenting concurrently may be incidental or could share the common metabolic pathway for becoming clinically overt. It is difficult to determine if the deficiency of vitamin B 3 which unmasked the thyroid deficiency or vice versa.


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