Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online: 492


ORIGINAL ARTICLE
Year : 2017  |  Volume : 14  |  Issue : 3  |  Page : 118-121

Evaluating thyroid function in the clinical laboratory


Department of Pathology, University of the West Indies, Mona, Kingston 7, Jamaica

Correspondence Address:
Donovan A McGrowder
Department of Pathology, University of the West Indies, Mona, Kingston 7
Jamaica
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/trp.trp_9_17

Rights and Permissions

Background: Thyroid disorders are common in clinical medicine and laboratory confirmation is essential, especially in cases where overt signs and symptoms are absent. The measurement of thyroid-stimulating hormone (TSH) is recommended as the best indicator of thyroid function and is utilized along with thyroxine (T4) and in some circumstances triiodothyronine (T3). Aim: The aim is to evaluate the relationship between TSH and free T4 (FT4), and TSH and FT3. Methods: Thyroid function tests (TFTs) – TSH, FT4, and FT3 – performed in the Chemical pathology laboratory from February to December 2015 were retrieved from the laboratory information management system. Results were classified based on TSH results into suppressed, mildly suppressed, normal, mildly elevated and elevated, and correlated with FT3 and FT4 results. Results were also categorized as overt hyperthyroidism, subclinical hyperthyroidism, normal, subclinical hypothyroidism, overt hypothyroidism, and “others” and compared based on age and gender. Results: FT4 and FT3 correlate best with TSH at suppressed and elevated levels. Mean TSH was significantly higher in males than in females only in those with normal FT4 and TSH. TSH was significantly higher in the 41–60 age group, with females in this group having significantly higher levels as compared to males. Conclusions: There is an inverse correlation between FT4 and TSH, and FT3 and TSH, especially significant at suppressed and elevated levels of TSH. Highest TSH levels were observed in women in the 41–60 age cohort.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1921    
    Printed80    
    Emailed0    
    PDF Downloaded203    
    Comments [Add]    

Recommend this journal