Thyroid Research and Practice

ORIGINAL ARTICLE
Year
: 2012  |  Volume : 9  |  Issue : 2  |  Page : 32--39

Fine-needle aspiration of the thyroid: A cytohistologic correlation with critical evaluation of discordant cases


Pinki Pandey1, Alok Dixit2, Nanak C Mahajan1 
1 Department of Pathology, M M Institute of Medical Sciences and Research, M M University, Mullana, Ambala, Haryana, India
2 Department of Pharmacology, M M Institute of Medical Sciences and Research, M M University, Mullana, Ambala, Haryana, India

Correspondence Address:
Pinki Pandey
E-15, MMIMSR Campus, M M University, Mullana- 133 203, Ambala, Haryana
India

Background: There is some DQgray zoneDQ of thyroid cytology, where the diagnostic efficacy declines sharply rendering it difficult to exactly categorize the lesion resulting in discrepancy. The aim of the study is to assess the accuracy of fine needle aspiration of the thyroid and critically evaluate the cytohistological discordant cases. Materials and Methods: A total of 447 patients with thyroid swelling were aspirated during a seven-year study period. Cases showing cytohistologic disparity were reevaluated for the detection of possible causes of failure. Results: In our study, cytohistologic concordance was achieved in 80.28% of the cases. Of the discordant cases, false positives accounted for 11.60% and false negatives for 9.8%. Suboptimal material and underdiagnosis of papillary carcinoma due to cystic degeneration were recognized as common pitfalls. Too much emphasis on cellularity and architectural pattern led to the erroneous false positive diagnoses. Conclusion: Strict adherence to adequacy criterion and meticulous examination of all the smears are of paramount importance in reducing discrepant cases.


How to cite this article:
Pandey P, Dixit A, Mahajan NC. Fine-needle aspiration of the thyroid: A cytohistologic correlation with critical evaluation of discordant cases.Thyroid Res Pract 2012;9:32-39


How to cite this URL:
Pandey P, Dixit A, Mahajan NC. Fine-needle aspiration of the thyroid: A cytohistologic correlation with critical evaluation of discordant cases. Thyroid Res Pract [serial online] 2012 [cited 2019 Jul 20 ];9:32-39
Available from: http://www.thetrp.net/article.asp?issn=0973-0354;year=2012;volume=9;issue=2;spage=32;epage=39;aulast=Pandey;type=0