Thyroid Research and Practice

REVIEW ARTICLE
Year
: 2013  |  Volume : 10  |  Issue : 2  |  Page : 47--55

Congenital hypothyroidism: Its profile in infancy


Sonal Kapoor1, Dheeraj Kapoor2, Vijai Kumar Kapoor3 
1 Department of Paediatrics, Leicester Royal Infirmary, Leicester, United Kingdom
2 Artemis Health Institute, Gurgaon, India
3 Childcare Centre, Katra Bazaar, Shikohabad, Uttar Pradesh, India

Correspondence Address:
Vijai Kumar Kapoor
Childcare Centre, Katra Bazaar, Shikohabad, Uttar Pradesh
India

Thyroid hormones play an important role in the physical development, neuronal growth and influence various metabolic processes of the newborn. Their deficiency or a defect in thyroid hormone receptor activity may present as congenital hypothyroidism. This may lead to irreversible mental and physical growth retardation. Interestingly majority of the neonates with congenital hypothyroidism appear to be normal. These facts led us to review this entity in infancy. Therefore, initiation of early treatment becomes essential. Levothyroxine is the drug of choice and its dosage should be adjusted with biochemical hormone assays. The untoward effects of congenital hypothyroidism are largely reversible, if treated before the age of 6 weeks, a very easily affordable help in curtailing the morbidity among these newborns. Genetic counseling and routine examination of siblings is very essential.


How to cite this article:
Kapoor S, Kapoor D, Kapoor VK. Congenital hypothyroidism: Its profile in infancy.Thyroid Res Pract 2013;10:47-55


How to cite this URL:
Kapoor S, Kapoor D, Kapoor VK. Congenital hypothyroidism: Its profile in infancy. Thyroid Res Pract [serial online] 2013 [cited 2020 Aug 10 ];10:47-55
Available from: http://www.thetrp.net/article.asp?issn=0973-0354;year=2013;volume=10;issue=2;spage=47;epage=55;aulast=Kapoor;type=0