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ORIGINAL ARTICLE
Year : 2010  |  Volume : 7  |  Issue : 3  |  Page : 76-83

Normal thyroid volume and its determinants in healthy middle age and above female population in central Kerala (Amrita Thyroid Survey)


1 Department of Endocrinology and Diabetes, Amrita Institute of Medical Sciences, Amrita ViswaVidyapeetham University, Kochi, Kerala, India
2 Department of Radiology, Amrita Institute of Medical Sciences, Amrita ViswaVidyapeetham University, Kochi, Kerala, India
3 Department of Biostatistics, Amrita Institute of Medical Sciences, Amrita ViswaVidyapeetham University, Kochi, Kerala, India

Correspondence Address:
V U Menon
Department of Endocrinology and Diabetes, Amrita Institute of Medical Sciences, Amrita ViswaVidyapeetham University, Kochi, Kerala
India
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Source of Support: None, Conflict of Interest: None


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Normal thyroid volume of adult population depends on many factors and may vary in different geographic areas; there is a lack of data from India. Aim of this study was to assess distribution of normal thyroid volume (TV) and its determinants in iodine sufficient healthy females of Kerala. Study was conducted as a cross sectional house to house survey among the females above 35 years of age in a randomly selected urban area in Kerala State, India. Selected subjects were interviewed, examined and blood and urine tests were done. TV was calculated using portable US scan ma苞hine. Among the 530 subject surveyed, 508 participated in the health checkup and from this 111 euthyroid iodine sufficient normal subjects were selected for further analysis. Mean age of the participants was 51.6 + 11.8 yrs and 53.2% were post衫enopausal. The mean TV of these subjects was 8.8 + 3.1 ml (Right lobe 4.65 + 1.8 and left lobe 4.1 + 1.6ml; p = 0.005) andthe97thcentileofTVwas 15.3 ml. Age and postmenopausal status had negative correlation (p<0.001) with TV whereas weight, height, lean body mass, body surface area, triceps and subscapularis skinfold thick要ess representing body fat showed significant positive correlations with TV. But after correcting for age only triceps and subscapularis skinfold thickness were showing significant (P 0.02 & 0.005) positive correlations with TV. Conclusion: The distribu負ion of normal TV of iodine sufficient Indian females is described and age, postmeno計ausal status had negative while body fat had positive correlations with TV.


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