| CASE REPORT |
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| Year : 2015 | Volume
: 12
| Issue : 1 | Page : 29-31 |
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Carbimazole-induced histomorphological changes simulating malignancy in toxic goiter
D Siva Ranjan, B Rama Mohan Rao, Epari Sanjeeva Rao
Department of Pathology, Konaseema Institute of Medical Sciences and Research Foundation, Amalapuram, Andhra Pradesh, India
Correspondence Address:
Dr. D Siva Ranjan
H.NO:C-108, Phase-2, Hill Colony, Vanasthalipuram, Hyderabad - 500 070
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0973-0354.147287
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Antithyroid drug therapy is still a widely used approach in the management of hyperthyroidism. Histomorphological changes of thyroid in toxic goiter, following carbimazole therapy are rarely documented. We present a case of 51-year-old female patient who clinically presented with features of thyromegaly. Initially a diagnosis of mutinodular goiter with follicular hyperplasia and in places raising even a suspicion of Hurthle cell neoplasm was made. Correlating the clinical details, history of drug intake, and histomorphological features; a final diagnosis of therapy (carbimazole) induced changes in toxic goiter was offered. |
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