Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online: 697

Year : 2018  |  Volume : 15  |  Issue : 2  |  Page : 60-64

Collision tumors of the thyroid: Review of literature and report of a case of papillary–Follicular collision tumor

Department of General and Laparoscopic Surgery, M.O.S.C. Medical College, Kolenchery, Kerala, India

Correspondence Address:
Vijy Paul Thomas
Department of General and Laparoscopic Surgery, M.O.S.C. Medical College, Kolenchery - 682 311, Kerala
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/trp.trp_6_18

Rights and Permissions

It is a known fact that thyroid malignancies are the most common of endocrine malignancies. Furthermore, differentiated thyroid malignancies including the papillary and follicular types are the most common among these malignancies of the thyroid. However, it is extremely uncommon to get a combination of two primary malignancies within the same thyroid gland. These combinations can be classified into collision tumors, mixed tumors, and composite tumors. Whenever such tumors have been described, they have almost always been combinations of papillary carcinoma and medullary carcinoma. Recently, a couple of cases of combinations of papillary and follicular carcinomas are being reported. It is difficult to completely explain the occurrence of such tumor types together in the same gland. Various theories have been proposed to explain this simultaneous occurrence such as the stem cell theory, collision theory, and the hostage theory. It is now accepted that these tumors should be considered more aggressive and having a higher risk of recurrence as compared to either of the tumors occurring independently. Treatment should be patient specific and is directed by the more aggressive of the tumors; however, no standardized protocols for diagnosis or treatment have evolved due to lack of significant information on their behavior.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded602    
    Comments [Add]    
    Cited by others 8    

Recommend this journal