Thyroid Research and Practice

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 12  |  Issue : 2  |  Page : 50--56

Thyroid dysfunction associated with excess fluoride intakes: Scope for primary prevention


Sandeep Sachdeva1, Juned Ahmed2, Balbir Singh2 
1 Department of Community Medicine, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India
2 Department of General Medicine, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India

Correspondence Address:
Sandeep Sachdeva
Epidemiologist cum Lecturer, 3/115 A, Durgabadi, Marris Road, Aligarh 202 002, Uttar Pradesh
India

Background: Preventable thyroid dysfunction has remained a neglected entity worldwide. Excess fluoride consumption over years leads to irreversible thyroid dysfunction. Materials and Methods: Subjects (N = 275) with thyroid dysfunction were recruited from medicine and endocrinology OPDs/wards and were thoroughly examined. The source and type of water consumed by these subjects was asked and sampled for fluoride analysis. Results: A majority (75%) of the subjects were females. Hypothyroidism including subclinical hypothyroidism was the major underlying dysfunction. Majority of the afflicted (53%) consumed ground water as their predominant drinking water source. Fluoride content was well above acceptable limits of potability (1mg/L) in ground water and this correlated positively with elevated serum thyroid stimulating hormone (TSH) and negatively with free T3 levels in blood. The correlation was statistically significant (P < 0.05). Conclusion: Excess of fluoride in drinking water was the plausible cause of hypothyroidism in study individuals. Fluoridation of water for prevention of dental caries is a policy that can be amended for the sake of this larger picture. Thyroid diseases deserve recognition as non-communicable diseases (NCDs) of public health importance.


How to cite this article:
Sachdeva S, Ahmed J, Singh B. Thyroid dysfunction associated with excess fluoride intakes: Scope for primary prevention.Thyroid Res Pract 2015;12:50-56


How to cite this URL:
Sachdeva S, Ahmed J, Singh B. Thyroid dysfunction associated with excess fluoride intakes: Scope for primary prevention. Thyroid Res Pract [serial online] 2015 [cited 2022 Dec 2 ];12:50-56
Available from: https://www.thetrp.net/article.asp?issn=0973-0354;year=2015;volume=12;issue=2;spage=50;epage=56;aulast=Sachdeva;type=0